Search results for "beam [neutrino]"

Design and development of safety and control systems in ATLAS

2021

El gran colisionador de hadrones, o LHC, es el acelerador de partículas más grande y potente del mundo. Ha sido construido por el CERN, la Organización Europea para la Investigación Nuclear, entre 1998 y 2008 en Ginebra, Suiza. Sucesivas mejoras en el LHC supondrán a partir de mediados del 2027 un incremento de la luminosidad, cuando pasará a llamarse High Luminosity LHC (HL-LHC). Esta tesis se divide en dos partes, por una parte la seguridad y operación de la infraestructura y por otra los sistemas de control y toma de datos. La primera parte de la tesis se dedica a la seguridad y operación de la infraestructura. Después de más de 10 años de funcionamiento, el riesgo de posibles fallos en …

Development and use of computational tools for modelling negative hydrogen ion source extraction systems

2013

Broad-beam transmission data for new brachytherapy sources, Tm-170 and Yb-169

2005

The characteristics of the radionuclides (170)Tm and (169)Yb are highly interesting for their use as high dose-rate brachytherapy sources. The introduction of brachytherapy equipment containing these sources will lead to smaller required thicknesses of the materials used in radiation protection barriers compared with the use of conventional sources such as (192)Ir and (137)Cs. The purpose of this study is to determine the required thicknesses of protection material for the design of the protecting walls. Using the Monte Carlo method, transmission data were derived for broad-beam geometries through lead and concrete barriers, from which the first half value layer and tenth value layer are ob…

Broad beam transmission data for the shielding of brachytherapy facilities

2008

Transpupillare Thermotherapie (TTT) zur Behandlung von Aderhautmetastasen

2001

Die transpupillare Thermotherapie (TTT) wird erfolgreich zur Behandlung kleiner Aderhautmelanome am hinteren Augenpol eingesetzt [9, 13, 14]. Wir berichten uber die erfolgreiche Behandlung von Aderhautmetastasen mittels TTT unter intravenoser Gabe von Indozyaningrun (ICG). Bei 3 Patienten mit systemisch metastasierenden Karzinomen (Osophagus-, Bronchial- und Mamma-Ca) wurden Aderhautfiliae in 4 Augen mit jeweils einer Sitzung TTT behandelt. Verwendet wurde ein Diodenlaser (810 nm) und Spotgrose 2–3 mm. Die Laserleistung (im Mittel 0,75W) wurde beginnend bei 0,3W in 50 mW Schritten fur jeweils 1 Minute erhoht, bis die Tumoroberflache eine grauweise Odembildung zeigte. Jeweils 1 Minute nach T…

Focal Therapy for Prostate Cancer: Complications and Their Treatment

2021

Focal therapy is a modern alternative to selectively treat a specific part of the prostate harboring clinically significant disease while preserving the rest of the gland. The aim of this therapeutic approach is to retain the oncological benefit of active treatment and to minimize the side-effects of common radical treatments. The oncological effectiveness of focal therapy is yet to be proven in long-term robust trials. In contrast, the toxicity profile is well-established in randomized controlled trials and multiple robust prospective cohort studies. This narrative review summarizes the relevant evidence on complications and their management after focal therapy. When compared to whole glan…

Understanding generation of multifunctional nanogels in chemical-free e-beam irradation synthesis

2018

Radiation engineered nanogels are the core of very promising theranostic nanodevoces. They can be produced starting from aqueous solutions of chemically inert polymers by pulsed e-beam irradiation.

Water-borne polymeric nanoparticles for glutathione-mediated intracellular delivery of anticancer drugs

2013

A new family of water-borne, biocompatible and carboxyl- functionalized nanogels was developed for glutathione- mediated delivery of anticancer drugs. Poly(N-vinyl- pyrrolidone)-co-acrylic acid nanogels were generated by e- beam irradiation of aqueous solutions of a crosslinkable polymer, using industrial-type linear accelerators and set- ups. Nanogels physico-chemical properties and colloidal stability, in a wide pH range, were investigated. In vitro cell studies proved that the nanogels are fully biocompatible and able to quantitatively bypass cellular membrane. An anticancer drug, doxorubicin (DOX), was linked to the carboxyl groups of NGs through a spacer containing a disulphide cleavab…

Rayleigh-instability-driven dewetting of thin Au and Ag films on indium-tin-oxide surface under nanosecond laser irradiations

2013

Investigations have been carried out on laser-beam-induced nanoparticle (NP) formation in thin (5 nm) Au and Ag films on indium-tin-oxide substrate. After the irradiation the films were observed to break-up into NPs through a dewetting mechanism. This mechanism was investigated as a Rayleigh-instability- driven process. In fact, for each used laser fluence, the resulting Au and Ag NPs' mean size and surface-to-surface mean distance were quantified and correlated between them in the framework of the Rayleigh-instability theory showing an excellent agreement. © The Institution of Engineering and Technology 2013.

Fractional viscoelastic transversally isotropic Timoshenko beam

2014

In this paper the viscoelastic behavior of pultruded beams has been examined. Pultruded beams are constituted by a polymer infilled with reinforcement in longitudinal direction, while in the orthogonal direction no fiber are present for technological reasons. As a consequence the material has two different behaviors in longitudinal and in orthogonal directions. It follows that pultruded beams are transversally isotropic, and the shear deformation may not be neglected. Based upon the previous observations and assuming for Creep and/or Relaxation test the power law, the constitutive equations are ruled by fractional operators. From constitutive laws, and assuming the Timoshenko beam theory to…